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The enzyme stabilizes the thiolate anion at neutral pH and combines this capability with providing a binding pocket for hydrophobic electrophiles at a site adjacent to the bound GSH 15

IP6K3, located near the major histocompatibility complex, has previously been linked to other autoimmune diseases such as Graves disease and rheumatoid arthritis, indicating its potential role in the development of autoimmunity and HT [20]

Since the observed peptides were actually determined from experimentally acquired spectra, the grouping could be considered to be guided by the spectra

[DOI] [PubMed] [Google Scholar] 1123.Giles J.T., Danielides S., Szklo M., Post W.S., Blumenthal R.S., Petri M., Schreiner P.J., Budoff M., Detrano R., Bathon J.M

Search strategies combined cannabinoid-related and vaping-related terms, and additional studies were identified through manual screening of reference lists